Inhibition of Tyrosinase Activity by 6- [(8 Z, 11 Z) -8, 11, 14-Pentadecatrienyl] salicylic Acid Derivatives
نویسندگان
چکیده
منابع مشابه
Synthesis of anacardic acids, 6-[8(Z),11(Z)-pentadecadienyl]salicylic acid and 6-[8(Z),11(Z),14-pentadecatrienyl]salicylic acid.
11-Chloro-3-methoxy-2-undecenal was synthesized from 8-bromooctanol, and an annelation reaction with this aldehyde and ethyl acetoacetate proceeded to give the ethyl 6-(8-chlorooctyl)salicylate. Ethyl 6-(8-chlorooctyl)salicylate was converted to ethyl 6-(7-formylheptyl)-2-methoxybenzoate through the iodide after protection of the phenolic hydroxyl group. Finally, the Wittig reaction with the al...
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Department of Radiation Oncology, Lineberger Comprehensive Cancer Center, Curriculum in Genetics and Molecular Biology, Department of Pharmacology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA * Current Address: The Hamner Institutes for Health Sciences, Research Triangle Park, NC § Current Address: Duke-NUS Graduate Medical School Singapore, 8 College R...
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In this paper, upper bounds on the minimum Euclidean weights of Type I codes over Z6 , and self-dual codes over Z8 and Z10 , are derived for modest lengths. The notion of extremality for Euclidean weights is also introduced. We construct new extremal self-dual codes over these rings. Most of these codes are obtained via the double circulant and quasitwisted constructions. New extremal odd unimo...
متن کامل12(R)-Hydroxy-5(Z),8(Z),10(E),14(Z)-eicosatetraenoic acid [12(R)-HETE], an arachidonic acid derivative, is an activator of the aryl hydrocarbon receptor.
The aryl hydrocarbon receptor (AHR) is a ligand-regulated transcription factor that can be activated by structurally diverse chemicals, ranging from environmental carcinogens to dietary metabolites. Evidence supporting a necessary role for the AHR in normal biology has been established; however, identification of key endogenous ligand/activator remains to be established. Here, we report the abi...
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ژورنال
عنوان ژورنال: Journal of Japan Oil Chemists' Society
سال: 1994
ISSN: 1884-2003
DOI: 10.5650/jos1956.43.574